Thousands of people with type 2 diabetes are enrolled in an NHS study of soups and shakes that has been shown to reverse the disease
A total of 5,000 patients in England have signed up to try the radical 12 month diet program to help them lose weight and restore their health.
Volunteers will be limited to just 800 calories a day – a third of the recommended daily allowance for an adult male and almost half that of a woman.
Your meals will be limited to mixed shakes, soup bowls, and health bars for three months before real, nutritious foods are reintroduced for the remaining nine months.
Type 2 diabetes is, in most cases, linked to being overweight or obese, not exercising enough, and consuming too much sugar.
The move is an extension of a smaller study after a 2018 Oxford University study found that nearly half of people who stuck to the soup and shake plan saw their diabetes go into remission after a year.
It is estimated that diabetes costs the healthcare system £ 10 billion a year, while nearly one in twenty general practitioner prescriptions is for the treatment of diabetes.
The condition is also one of the biggest risk factors for coronavirus death. Around a third of the UK's Covid 19 victims also suffer from this disease.
People with type 2 diabetes are offered soup and shakes the weight loss plan on the NHS (file)
A study of the Soup and Shake Diet found that it works for most people looking to lose weight and is effective because it uses fewer calories than it burns.
The 5,000 volunteers diagnosed with diabetes in the past six years will begin the programs today.
You will be asked to swap food for mixed meal replacement shakes and soups for three months.
For the remainder of the year, they are coached by nutritionists who will help bring normal, nutritious meals back into their diet and increase their level of exercise.
CAN DIABETS BE REVERSED?
It is possible to put type 2 diabetes into "remission" if the blood sugar level is below the diabetes range and the patient no longer needs to take medication.
The term "reversed" is not used often as it implies a cure. However, there is no guarantee that a person with type 2 diabetes will be free from the disease forever.
The strongest evidence of achieving type 2 diabetes remission suggests weight loss in people who carry extra weight or are obese.
Scientists believe that storing too much fat in the liver and pancreas affects the development of type 2 diabetes, and losing that fat may help put the disease into remission, according to Diabetes.org.
The website says, "In fact, losing about 50 pounds increases the likelihood of type 2 diabetes remission significantly."
It is easier to bring diabetes into remission closer to diagnosis.
Professor Jonathan Valabhji, the NHS National Clinical Director on Diabetes and Obesity, said, 'This is the latest example of how the NHS is rapidly applying the latest evidence-based treatments to help people stay healthy as part of our long-term plan and maintain a healthy weight and avoid serious illnesses.
"There has never been a more important time to lose weight and put your type 2 diabetes into remission, so it is good news for thousands of people across the country that practical, supportive interventions like this are increasing in the NHS Are available."
Bridget Turner, director of policy campaigns and improvements for Diabetes UK, said the program was "an important first step" for patients to gain access to a remission program within the NHS.
She said, “We know that some people with type 2 diabetes want and need support from healthcare professionals in order to lose weight effectively, and now that these programs are being piloted across the NHS, they will.
“People with type 2 diabetes who have put their diabetes into remission often tell us how it changed their lives.
"We are delighted that others now have an equal opportunity and hope it won't be too long before more removal programs are rolled out across the country."
Type 2 diabetes is the most common form of the disease, affecting 90 percent of all 4.7 million diabetics in the UK.
Type 1 diabetes is caused when the pancreas doesn't make enough insulin to regulate the body's blood sugar levels and is generally caused by genetics.
While Type 2 is linked to obesity and too much sugar, the body becomes insulin resistant.
Since type 2 is mainly caused by people's lifestyle, it can be reversed through low-calorie and low-sugar diets.
The trial comes just over a month after the Boris Johnson administration launched a campaign to fight obesity after the prime minister realized that his own weight contributed to ending up in intensive care when he was himself infected with coronavirus.
TYPE 2 DIABETS CAN BE TRIGGERED BY A WEIGHT THRESHOLD
According to one study, every person has a goal weight to stay below or they are at risk of type 2 diabetes.
Researchers who studied half a million Britons said people seem to have a personal body mass index (BMI) threshold that triggers abnormal blood sugar levels.
They claim millions of people could avoid developing diabetes if they kept their weight within a healthy range below this goal.
And for those diagnosed with type 2 diabetes, the condition can be completely reversed by aggressively reducing calories, the scientists say.
Because the BMI is specific to each individual, everyone has a different threshold at which they are classified as overweight or obese and at risk of developing diabetes.
For example, a 182 cm (6 foot) man would be considered healthy if he weighed 82 kg (13 stones), while a 164 cm (5 ft 4 in) woman would be considered obese.
BMI is a rough measure of height and weight used to determine whether someone is a healthy weight.
The researchers haven't given exact numbers, but they say their results will help doctors identify who is most at risk of developing diabetes based on their weight.
The study, carried out by the University of Cambridge, looked at 445,765 people in the UK biobank.
Scientists found that people with severe obesity who had a BMI of 35 or greater had an 11-fold increased risk of diabetes, compared to the lowest group with an average BMI of 21.7.
This was the case even when genetic predispositions to the condition – such as a family history of diabetes – were taken into account.
Lead researcher Professor Brian Ference presented the results at the European Society of Cardiology (ESC) annual congress today and said the study was pretty clear.
"The results show that BMI is a much stronger risk factor for diabetes than genetic makeup," he said.
"This suggests that when people exceed a certain BMI threshold, regardless of how long they're overweight, the chances of developing diabetes increase."
Mr Johnson said that since recovering from the terminal illness, he has focused on getting fitter through morning runs with his dog, Dilyn, and that he ran with a personal trainer in London last week.
He has urged the nation to follow his example, insisting that the government's "better health strategy" will help people "lose weight" and better protect the NHS.
Great Britain is the second fattest country in Europe. According to the government, two-thirds of adults are over a healthy weight, and every third child, ages 10-11, is overweight or obese.
The government's new strategy to fight obesity will seek to end confectionery at the checkout counter and ban advertising of foods high in fat, sugar and salt on TV before 9 p.m.
Offers like "Buy One Get One Free" on unhealthy foods will also be banned, while alcoholic beverages may soon have to declare their calorie content.
It will stop placing sugary and greasy items in prominent locations in stores, including at checkouts and entrances, as well as online.
Instead, stores are encouraged to encourage healthier choices and offer more discounts on healthy foods like fruits and vegetables.
The government will also hold a consultation on whether the ban on online advertising should apply to foods high in salt, sugar and fat at any time of the day.
Mr Johnson said in a video posted on Twitter when the strategy launched in July that "how many people am I struggling with my weight" and he "has been wanting to lose weight for ages".
"But since I recovered from the coronavirus, I've steadily improved my fitness," he said.
“I don't want to be overly demanding because I've just focused on it, but I'm more than a rock down.
The diabetes trial comes amid Prime Minister Boris Johnson's pledge to help the UK lose weight as he has improved his health himself since being exposed to a coronavirus that left him in intensive care (pictured in Buckinghamshire) .
“When I went to the intensive care unit when I was really sick, I was way overweight. I'm only about five feet ten and I was too fat.
“I start the day with a run with the dog – a pretty gentle run, but now it gets faster the fitter I get.
“The great thing about running a run at the beginning of the day is that nothing could be worse for the rest of the day.
"If you work really hard, if you really start exercising, the rest of the day will be a breeze."
Mr Johnson said the "biggest benefit" of losing weight is that you "feel much better" and feel "full of energy".
He continued, “The other thing, of course, is if you can drop your weight a little and protect your health, you will protect the NHS too.
“Gyms are great, but you don't need a gym. These days there are amazing things on your phone, amazing apps, and amazing trainers to watch on YouTube.
“What we're doing now with our strategy for better health is just trying to help people get a little bit of weight down – hopefully not overly bossy or nanny.
"We want them to really sympathize with the people, the struggles people face with their weight, the struggles everyone faces, the struggles that many, many people face, lose weight and just be helpful." to be."
As the effects of the coronavirus on obese people have become clear, scientists have begun human trials of a "potentially life-saving" treatment for coronavirus patients with diabetes.
Doctors will test a drug called AZD1656, made by AstraZeneca, to see if it can reduce the risk of developing serious illness or killing infected diabetics.
Patients with type 1 or type 2 diabetes have up to three times the risk of death when they get Covid-19. A number of studies have shown this.
NHS data shows that of all the specifically categorized diseases (i.e., not "other"), diabetes was the most common underlying condition in people who died of Covid-19 by Aug. 20, accounting for more than a quarter of all victims
The experimental drug tested is called a glucose kinase activator. It was developed to lower blood sugar and is still in the clinical trial phase for patients with type 2 diabetes and kidney transplants.
What are Type 1 and Type 2 Diabetes?
Type 1 diabetes is an autoimmune disease in which the insulin-producing cells in the pancreas are destroyed and the body is unable to produce enough insulin to regulate blood sugar levels.
If the amount of glucose in the blood is too high, it can cause serious damage to the organs of the body over time.
Patients diagnosed with Type 1 are treated with insulin.
It is sometimes referred to as adolescent diabetes, but the term is considered obsolete as the condition can develop at any age.
Type 2 diabetes is a condition that causes a person's blood sugar to become too high.
Over 4 million people in the UK are believed to have diabetes.
Type 2 diabetes is linked to being overweight and you are more likely to get it if it runs through the family.
The condition means that the body is not responding properly to insulin – the hormone that controls the absorption of sugar into the blood – and cannot properly regulate the level of sugar glucose in the blood.
Excess fat in the liver increases the risk of developing type 2 diabetes, as the build-up makes it difficult to control glucose levels and makes the body more resistant to insulin.
Weight loss is key to reducing liver fat and controlling symptoms.
Up to 150 Covid-19 patients from NHS hospitals will be tested over the next four months.
The researchers hope this will prevent diabetic immune systems from overreacting to the coronavirus, which can be fatal.
The company that conducted the study on hospitalized patients said it was "potentially lifesaving" and "has the potential to make a big difference".
Although the reason people with diabetes are at higher risk for coronavirus is not fully understood, it is believed that it may be due to a dysfunction in the immune system.
Those with the diseases that mean the body is unable to control blood sugar levels are generally at higher risk of getting infected.
Wounds and diseases are slower to heal in people with diabetes, and there is a higher risk of complications because high sugar levels can damage vital molecules in the immune system.
If they catch Covid-19 patients with these conditions, it seems more likely that they will develop pneumonia or have a fatal immune system overreaction.
This applies to both type 1 diabetes, which cannot be prevented, and type 2 diabetes, which is often caused by an unhealthy lifestyle – poor diet and no exercise.
Studies suggest that people with type 1 diabetes are more than three times more likely to die from Covid-19 than healthy people, and people with type 2 diabetes are twice as likely to die, according to the NHS.
Scientists from Excalibur Healthcare Services, which organized and funded the study, hope AZD1656 will prevent diabetic immune systems from overreacting to Covid-19.
The glucokinase activator from AstraZeneca of Cambridge was developed to lower blood sugar levels in people with diabetes.
Tests have shown that it is safe and there are mass human trials to see if it works effectively. It is aimed at people with type 2 diabetes and people who have had kidney transplants.
The coronavirus study, named ARCADIA, is being carried out with the help of the UK Medical Research Charity, St. George Street.
The drug is being tested in coronavirus patients in UK hospitals with "mild to moderate" symptoms.
If it worked, the company suggested the drug could be prescribed by a general practitioner to diabetics who have early symptoms of Covid-19.
The ARCADIA study was approved by the State Medicines and Health Products Regulatory Agency (MHRA).
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