Newcastle is now at the epicenter of England's coronavirus after infections in the city rose 60 percent to 250 cases per 100,000.
And the rise in infections in the northwest has put Knowsley and Liverpool in second and third place of the hardest hit countries in the country, after rising 50 percent in both cities. You now have 246 and 239 cases per 100,000, respectively.
But Bolton, who was at the center of the England outbreak for four weeks, fell out of the top 5 after falling 10 percent to 180 per 100,000 on 10 occasions.
The case in the city of Greater Manchester suggests that tough Covid-19 restrictions have come into effect, offering a glimmer of hope to other regions facing draconian measures.
Despite warnings of further restrictions, London has no counties in the 50 most infected areas of England, highlighting the divide between north and south coronaviruses in England. Redbridge has the highest rate at 56 cases per 100,000 after the local authority saw infections rise by 40 percent.
Public Health England data is based on Covid-19 swabs performed nationwide between August 21 and September 27, and daily indicators through September 29 showing up to 1 in 14 tests now are positive. Experts fear infections across the country could be higher than the numbers suggest.
All ten of England's top coronavirus hotspots are in the north and show the north-south divide
This map shows areas with the fastest growth in coronavirus cases, with the north being the fastest growing along with some areas of London
Manchester was the fourth largest hotspot in the country, the data shows after cases rose 36 percent to 200 per 100,000.
And St. Helens on Merseyside shot up to the fifth most infected area in England after the infection rate rose 82 percent, bringing the rate to 200 per 100,000.
When the country was hit by increasing Covid-19 infections:
- Halton in Cheshire rose to sixth place in the UK after cases rose 22 percent to 195 per 100,000.
- Sunderland reached eight positions behind Bolton after a 42 percent increase hit 172 cases per 100,000.
- Sefton in Merseyside was next with a 64 percent increase, taking the fall rate to 167 per 100,000, while Bury in Greater Manchester was tenth with a six percent increase and 166 per 100,000.
- Middlesbrough saw one of the highest increases in coronavirus cases in the country, after infections rose 136 percent to 116 per 100,000.
- In Darlington, infections rose 210 percent and the case rate rose to 90 per 100,000.
Top 15 Coronavirus Hotspots in the UK
- Newcastle250 cases per 100,000, UP 60 percent
- Knowsley247 cases per 100,000, UP 53 percent
- Liverpool239 cases per 100,000, UP 51 percent
- Manchester200 cases per 100,000, UP 36 percent
- St. Helens200 cases per 100,000, UP 82 percent
- Wait195 cases per 100,000, UP 22 percent
- Bolton180 cases per 100,000, 10 percent
- Sunderland172 cases per 100,000, UP 42 percent
- Sefton167 cases per 100,000, UP 64 percent
- To bury167 cases per 100,000, UP six percent
- South Tyneside166 cases per 100,000, seven percent
- Warrington155 cases per 100,000, UP 50 percent
- Rochdale151 cases per 100,000, UP 22 percent
- Oldham150 cases per 100,000, UP three percent
- Salford146 cases per 100,000, UP 16 percent
The lowest infection rates were observed in the Isle of Wight, where the NHS Covid app was first tested. The rate is 4 per 100,000. The second lowest was Suffolk with 6.1 cases per 100,000, followed by Dorset with 7.7 per 100,000.
The government and local health officials have tightened coronavirus restrictions in areas with higher cases to help contain the spiraling infections.
Liverpool, Warrington, Hartlepool and Middlesbrough were the newest cities to face tougher lockdown restrictions yesterday when officials tried to lock assembly cases.
The rules require people not to participate in professional or amateur sports events, not to travel unless required to go to school or work, and to visit nursing homes only in exceptional cases.
The regions follow much of the Northwest and Northeast in tightened restrictions amid an ever-growing outbreak in the north of England.
The latest data shows the strong coronavirus divide in the north and south of England, with 49 of the most heavily infected regions in the north of the Midlands.
Slough, on the outskirts of Windsor, was the only local authority in the south to reach the top 50 with 61 cases per 100,000 after a 200 percent increase.
Experts have suggested that this breakdown is due to a combination of factors including weather, levels of deprivation, and differences in levels of immunity between regions.
The south-east and London were the driest, warmest and sunniest areas in the UK in August, according to the Met Office, as summer came to a bleak end in most of the country.
Dr. Andrew Preston, an infectious disease expert at the University of Bath, told MailOnline it was "perfectly reasonable" to link this to the occurrence of coronavirus cases.
It is believed that the showers and cooler weather encouraged people to spend longer in the north, where the virus can spread better.
London's top ten coronavirus hotspots
- Redbridge57 cases per 100,000, UP 42 percent
- Bark and Dagenham53 cases per 100.00, UP 64 percent
- Hounslow50 cases per 100,000, UP 139 percent
- Newham49 cases per 100,000, UP 77 percent
- Tower hamlet46 cases per 100,000, UP 39 percent
- Havering46 cases per 100,000, UP 68 percent
- Hillingdon46 cases per 100,000, UP 80 percent
- Ealing43 cases per 100,000, UP 105 percent
- Brent40 cases per 100,000, UP 95 percent
- Hammersmith and Fulham36 cases per 100,000, UP 97 percent
In some cases, the level of deprivation may also have increased as it makes people less able to self-isolate or work from home, putting them at greater risk of spreading and the Sickness to get sick.
Middlesbrough, Liverpool, Knowsley, Hull and Manchester in the north have the highest levels of deprivation in the country, according to a government report.
However, other experts said the difference could be due to immunity – some argued that at the height of the outbreak, which was mainly in the south, the virus infected up to 100,000 people a day.
This would mean it has a higher rate of immunity to the virus than the North, which puts pressure on every subsequent second wave.
Boris Johnson and his two top scientific advisors released an impressive set of statistics earlier this week exposing the various coronavirus outbreaks in the north and south.
The northwest is currently diagnosed with an average of 1,595 cases of Covid-19 each day, compared to just 150 in the southwest, while Yorkshire, Humber and the northeast have the second highest infection rates.
All 10 areas with the worst per capita ratios are in the north, while eight out of ten areas with the lowest are in the south. Professor Whitty said there was a "strong concentration" of coronavirus towards the top of England.