TOP TRENDING

Matt Hancock offers to broadcast the coronavirus vaccine live with Piers Morgan to prove its safety


Boris Johnson could be vaccinated live on TV to prove the sting is safe, his press secretary suggested today.

Allegra Stratton said: “We all know the character of the Prime Minister, I don't think he would rule that out.

"But we also know that he doesn't want to take a push that is intended for someone who is extremely vulnerable and clinically vulnerable and who should be facing him."

UK regulators were the first in the world to approve the vaccine developed by Pfizer and BioNTech, paving the way for the jabs to start next week.

People at highest risk for coronavirus – those over 80 and residents of nursing homes – and health workers will come first.

However, Good Morning UK host Piers Morgan urged politicians to get the vaccine early – and get it on the air – to encourage fearful Brits to follow suit.

Health Secretary Matt Hancock took up his suggestion that both should take the thrust in front of the camera, adding that it would be worth it if it convinced people of its safety.

Similarly, Scottish First Minister Nicola Sturgeon said at her daily conference, "If I thought it would help convince anyone, I will".

Boris Johnson (pictured tonight of # 10) could be vaccinated live on TV to prove the sting is safe, his press secretary suggested today

At her daily conference, Scottish Prime Minister Nicola Sturgeon said: "If I thought it would help convince anyone, I will."

The Minister of Health picked up Piers Morgan at his suggestion to take the thrust on camera, adding that it would be “worth it” for him to chase people down for his safety

Matt Hancock (right) picked up on Piers Morgan's suggestion to take the thrust on camera, adding that it would be “worth it” for him to chase people after his safety. Similarly, Nicola Sturgeon (left) said, "If I thought it would help convince someone, I'll do it."

Mr Hancock stressed earlier today that the order in which people receive a vaccine depends on clinical needs.

Morgan told Good Morning Britain's Minister of Health, “I'll be with you anytime next week if we can. Let's do it together, live on the air. It would be powerful, it would send the right message. & # 39;

Mr. Hancock said, “Well, we'd have to get this approved because of course there is clinical need prioritization, and luckily, as a healthy middle-aged man, you're not high on the prioritization list.

“But if we can approve this and people think it's reasonable, then I'm ready, because once the MHRA approves a vaccine, they only do so if it's safe.

"And if that can help someone else convince someone to take the vaccine, then I think it's worth it."

That the Prime Minister should be at the head of the queue for a vaccine to demonstrate his safety was touted yesterday by a senior Tory MP.

In the House of Commons, former minister Sir Desmond Swayne also said high profile celebrities should throw their weight behind the vaccination campaign.

He said: “The way to get people to get a vaccine is to line up the entire government and its ministers and dependents and have them taken first and then all the Luvvies, the icons of popular culture, on the air to bring sings his praise. & # 39;

Vials are seen when an employee at the Pfizer manufacturing facility in Kalamazoo, Michigan works on the coronavirus vaccine

Vials are seen when an employee at the Pfizer manufacturing facility in Kalamazoo, Michigan works on the coronavirus vaccine

The Minister of Health stressed that the order in which people were given a vaccine would depend on clinical needs, but told Mr Morgan (pictured) that a vaccination on television "would be worth it" if it convinced people of its safety

The Minister of Health stressed that the order in which people were given a vaccine would depend on clinical needs, but told Mr Morgan (pictured) that a vaccination on television "would be worth it" if it convinced people of its safety

But in November England's assistant chief physician Jonathan Van-Tam said it was "clearly not right" for people to skip the line.

When asked whether high-profile government officials like himself or the Prime Minister should first take a vaccine to prove to the public that it is safe, he suggested that the "mother test" – whether you would press an elderly relative to do it – is important be.

"If I could rightly and morally be at the top of the queue, I would do so because I absolutely trust the MHRA's judgment on safety and effectiveness," he said.

"But that is clearly not right – we need to target the most risky people in society, and that is how it should be with our system."

Tonight, Mr Johnson stressed that a successful introduction of the vaccine is the key to a return to normal life.

At a press conference # 10, he said: “While we are doing all this, we no longer rest on the mere hope that we can go back to normal in the spring of next year, but on the sure knowledge that we will be successful and together will reclaim our lives and all the things in our lives that we love. & # 39;

A truck leaves Pfizer's manufacturing facility in Puurs, Belgium this morning after the American company's Covid-19 vaccine was approved in the UK. It is not clear whether the truck pictured transported the bumps

A truck leaves Pfizer's manufacturing facility in Puurs, Belgium this morning after the American company's Covid-19 vaccine was approved in the UK. It is not clear whether the truck pictured transported the bumps

It was revealed today that frontline NHS workers could skip nursing homes to come first for Pfizer / BioNTech's vaccine.

The Joint Committee on Vaccination and Immunization (JCVI) today published its list of priorities for Covid-19, advising that nursing home residents and the staff treating them should be the first groups to be vaccinated.

However, officials warned they could not guarantee that nursing homes would receive the vaccine before anyone else, admitting that "whether or not this is actually feasible depends on the deployment and implementation".

Pfizer / BioNTech's vaccine has been shown to block 95 percent of Covid-19 infections in late-stage studies, with younger volunteers and those over 65 who are most at risk of Covid being equally effective.

However, transporting and storing the vaccine in nursing homes poses logistical challenges as it has to be stored and transported at -70 ° C.

To keep the dosage of the shock at this extremely low temperature, they have to be packed with dry ice and placed in a special transport box the size of a suitcase.

These containers can prevent the vaccines from spoiling for 10 days if left unopened.

Once the batches arrive at the vaccination centers, they can be stored in standard medical refrigerators between 2 ° C and 8 ° C for up to five days or in their shipping boxes for up to 30 days if the containers are filled with dry ice at least once a week .

Fifty NHS hospitals in England are already equipped with super-cold freezers that can keep the vaccine at -70 ° C so health workers could be vaccinated first.

However, the makers of the shock have questioned claims that the shock is difficult to transport, claiming that it can be held between 2 ° C and 8 ° C for six hours while in transit without starting off.

Matt Hancock said 800,000 doses of the Pfizer vaccine – enough to vaccinate 400,000 people since it is given in two shots – will be made available "starting next week" as he said the end of the pandemic was now in sight .

The Minister of Health said, "We can see dawn in the distance, but we have to get through by morning."

The UK has ordered a total of 40 million doses of Pfizer's vaccine, 10 million of which are due by the end of 2020 and the rest by next year.

Boris Johnson also hailed the vaccine approval this morning, saying it would allow us to regain our lives and get the economy going again.

Mass vaccination is seen as the only way to end the perpetual opening and closing of society through draconian lockdowns that have devastated the economy and general health.

Revealed: EVERYTHING You Need To Know About Pfizer's Covid Vaccine, From The Science Of How The 95% Active Ingredient Works, How It Costs Five Times More Than Oxford, And From The 50 Hospitals List, Next Week should begin with the introduction

How many cans of Pfizer has the UK bought?

The UK has received 40 million doses of the Pfizer / BioNTech vaccine, with 10 million due in the UK by the end of the year. Matt Hancock announced that 800,000 cans will be available next week.

Patients need two doses, which means number 10 has only secured enough doses for about a third of the UK.

However, it is likely that other vaccines, including one from Oxford University, from which Britain bought 100 million doses, will be approved in the coming weeks and months.

How long does it protect you?

Regulators announced today that there was evidence of "partial immunity" just seven days after the first dose, offering a glimmer of hope that the roll-out could have an impact starting next week before Christmas.

However, they insisted that the best immunity comes seven days after the second dose given three weeks after the first.

It remains a mystery how long immunity to Covid lasts. Top scientists warn that people like the flu may need to be vaccinated against the disease every winter.

How is a vaccine introduced?

Behind the scenes, work has been going on to ensure that NHS staff will be ready to start delivering vaccines to those most at risk by early December.

Nightingale hospitals and sports stadiums have been prepared as sites for mass vaccination clinics, while general practitioners and pharmacists will also be involved in the mammoth army-backed operation to deliver the sting.

Mr Hancock also told Sky News that "50 hospitals across the country are already set up and waiting to receive the vaccine once it's approved".

The government has also put in place new regulations that will allow more health care workers – and NHS volunteers – to give flu and potential Covid-19 vaccines. You will be monitored by a healthcare professional.

NHS England yesterday evening released its full contract specification for family doctor offices that deliver Covid puffs vaccine without wasting.

A letter sent to all practices indicates that some staff may need to vaccinate patients on Christmas Day. It is expected that vaccination sites can deliver at least 1,000 shocks per week. The vaccination contract begins next Tuesday and GPs will receive £ 25.16 for every two puffs they give.

Volunteers with no medical training can use the GoodSAM app to get involved in injections with St. John Ambulance. The role description states: “Voluntary vaccines are trained to give a patient a vaccination. You are also ready to act if a patient experiences a side effect. & # 39;

Attempts are also made to volunteer for vaccination care. They help patients get to the right place for their thrust and are available to provide first aid if someone is uncomfortable.

Voluntary patient advocates, the third type of caregiver, will "focus on patient welfare through their experience".

What kind of vaccine is it?

The sting is known as a messenger RNA (mRNA) vaccine.

Traditional vaccines are made using weakened forms of the virus, but mRNAs only use the virus' genetic code.

An mRNA vaccine is injected into the body, where it enters the cells and prompts them to produce antigens. These antigens are recognized by the immune system and prepare it to fight the coronavirus.

What are the benefits of this type of vaccine?

No actual virus is needed to make an mRNA vaccine. This means that the speed at which it can be made is accelerated dramatically. As a result, mRNA vaccines have been touted as a potentially quick fix to new infectious disease outbreaks.

In theory, they can also be modified relatively quickly if, for example, a virus develops mutations and begins to change. mRNA vaccines are also cheaper to make than traditional vaccines, although both will play important roles in fighting Covid-19.

Are there any disadvantages?

A disadvantage of mRNA vaccines is that they have to be stored in extremely cold temperatures and cannot be easily transported.

Pfizer's Covid vaccine has to be stored in special suitcase-like storage boxes at minus 70 ° C – about four times colder than a household freezer. Dedicated GPS trackers mean that the temperature of the Pfizer / BioNTech vaccine can be remotely monitored to ensure it stays at the right heat to maintain its effectiveness.

Details of how the vaccine might be transported and stored came out of concerns that the NHS might have difficulty handling a vaccine that would have to be stored at minus 70 ° C.

Chris Hopson, Managing Director of NHS Providers, said, "The logistics for managing the Pfizer / BioNTech push are impressive."

Mr Hancock said while the rollout was not "easy" he was confident that the NHS could deliver the vaccine despite the logistics involved.

Pfizer has developed a suitcase-sized container that keeps cans of dry ice at minus 70 ° C for up to 10 days.

Each of the containers, known as the "dispatcher", holds around 1,000 cans and is equipped with heat sensors so that the pharmaceutical company can track the location and temperature of the frozen vaccine bottles.

The thermal shipping systems can be charged with dry ice if needed, Pfizer said. Vaccines are sent by air and road, but not by boat due to time constraints.

And once the vaccine has been transported, it can be stored in the refrigerator at 2-8 ° C for up to five days – which is quite possible in a standard medicine refrigerator in a general practitioner’s practice.

Are you sure?

All vaccines are rigorously tested and monitored by experienced regulators.

Some believe that mRNA vaccines are safer for the patient as they do not rely on any element of the virus to be injected into the body. mRNA vaccines were tested in the laboratory and on animals before moving to human studies.

The human mRNA vaccine trials, involving tens of thousands of people around the world, have been going on since early 2020 to show that they are safe and effective.

Pfizer will continue to collect data on safety and long-term outcomes from participants for two years.

HOW DO THE OXFORD, MODERNA AND PFIZER / BIONTECH Vaccines compare?

Moderna and Pfizer / BioNTech have both released interim clinical trial results for their end-stage vaccines, both of which indicate that they are extremely effective.

Oxford University has published the results of its second phase, showing that the sting induces an immune response and is safe to use. It's not yet clear how well it protects against coronavirus in the real world.

How to Compare:

PFIZER (US) & BIONTECH (DE)

mRNA vaccine – Genetic material from the coronavirus is injected to stimulate the immune system to make "spike" proteins and learn how to attack them.

mRNA vaccine – both Moderna, Pfizer and BioNTech vaccines work the same way.

Recombinant Viral Vector Vaccine – A harmless cold virus taken from chimpanzees has been engineered to produce the "spike" proteins and look like the coronavirus.

94.5% effective (90 positive in the placebo group, 5 positive in the vaccine group).

95% effective (160 positive in the placebo group, 8 positive in the vaccine group).

62% – 90% effective, depending on the dosage.

Moderna confirmed that countries placing smaller orders, such as the UK's five million cans, will pay between £ 24 and £ 28 per dose. The US has secured 100 million doses for $ 1.525 billion (£ 1.16 billion), suggesting it will cost $ 15.25 (11.57 pounds) per dose.

The US pays $ 1.95 billion (£ 1.48 billion) for the first 100 million doses, which is the equivalent of $ 19.50 (£ 14.80) per dose.

Estimated to cost £ 2.23 per dose. The UK's full 100 million dose supply could add up to just £ 223 million.

The UK has ordered five million cans that will be available from March 2021. Moderna will produce 20 million cans this year, which is expected to remain in the US.

The UK has already ordered 40 million cans, 10 million of which could be available in 2020. The first vaccinations are expected in December.

The UK has already ordered 100 million cans and is expected to come first to get the cans once approved.

What side effects does it cause?

Moderna said the vaccine was "generally safe and well tolerated". Most of the side effects were mild or moderate, but included pain, fatigue and headache, which "generally" were short-lived.

Pfizer and BioNTech did not provide a breakdown of the side effects, but said the Data Monitoring Committee "did not report any serious safety concerns."

Oxford said there were no serious safety concerns. Mild side effects were relatively common in small studies. Many participants reported that their arm hurt after the shock and that they later suffered from headache, fatigue, or muscle pain. Further data is collected.

HOW IS A VACCINE APPROVED SO QUICKLY?

Traditionally, vaccines can take years to research and develop. How was a vaccine approved for rapid use?

How did that come about so quickly?

The schedule for the development and approval of a Covid vaccine was shortened due to the coronavirus crisis.

What is the common procedure for developing a vaccine?

Vaccine development traditionally takes several years and involves various processes, including the design and development phases, followed by clinical trials, which in and of themselves need to be approved before they even begin.

The experiments take place in three successive phases – also known as phases. Research will show whether a vaccine creates antibodies but also protects people from disease. They also identify any security issues.

After the studies are complete, the information gathered by the researchers is sent to the regulators for review.

This is thoroughly analyzed by clinicians and scientists before it is approved for wide use.

After regulatory approval, people can get the vaccine.

Is that different because of the pandemic?

In the studies for a Covid vaccine, the procedure looks a little different.

While the early design and development phases look similar, the clinical trial phases have overlapped – rather than one after the other.

But doesn't that mean security is at risk?

Although some phases of the clinical trial process were parallel rather than sequential, the safety checks were still the same as for any new drug.

The Regulatory Authority for Medicines and Health Products (MHRA) has adopted the term "safety is our catchphrase".

The regulatory authorities have announced that they will "strictly assess" the data and evidence submitted regarding the safety, quality and effectiveness of the vaccine.

In most clinical trials, safety issues are usually identified in the first two to three months – a period that has already passed for most vaccine front-runners.

How do regulators act so quickly?

The regulators have carried out ongoing reviews, which means they have been given access to the data as the scientists work, rather than going through tons of information at the end of the studies.

A rolling review of vaccine data began a few months ago.

This means regulators can start reviewing scientific data earlier than before, which in turn means the approval process can be accelerated.

Regulators sometimes have thousands of pages of information to go through with a fine tooth comb – which understandably takes time.

As soon as all the data available on the vaccine are available, the MHRA experts will carefully and scientifically review the safety, quality and effectiveness data – how they protect people from Covid-19 and what level of protection they offer.

Once this is done, advice will be sought from the government's independent advisory body, the Commission for Medicinal Products for Human Use (CHM).

What does "approved for use" mean?

In order for a medicine to be used in the UK, it must be licensed. This means that all rigorous safety and efficacy tests have been passed and the regulatory authorities are confident of the results of the clinical trials.

By reviewing the data as it becomes available, the MHRA can come to an earlier opinion on whether or not the medicine or vaccine should be approved without compromising the thoroughness of its review.

What data will the regulator check?

The information provided to the MHRA includes what the vaccine contains, how it works in the body, how well it works, what side effects it has and who it is for.

This data must include the results of all animal and human clinical studies, manufacturing and quality controls, batch production consistency, and review of the final product specification.

The factories that manufacture the vaccines are also inspected before a license can be granted to ensure that the product supplied is of the same consistently high standard.

(tagsToTranslate) Dailymail (t) Nachrichten (t) Piers Morgan (t) Good Morning Great Britain (t) Coronavirus (t) Pfizer