CBD Helps the Mind: A study shows that cannabidiol improves blood flow to parts of the brain associated with memory and decision-making
- The researchers gave 15 participants with no history of cannabis use 600 mg of CBD on various occasions for a week and then 600 mg of a placebo
- CBD (Cannabidoil) is the main non-psychoactive ingredient in marijuana that is believed to be responsible for therapeutic effects such as pain relief
- MRI studies showed that CBD increased blood flow to the hippocampus, which is responsible for memories, and the orbitofrontal cortex, which is responsible for decision-making
- The team says this could offer therapies for those who suffer from conditions that affect memory, such as Alzheimer's disease
Just one dose of Cannabidoil (CBD) has been shown to improve blood flow to parts of the brain, a new small study suggests.
The researchers found that the main non-psychoactive ingredient in marijuana increased blood flow to the hippocampus, the area of the brain responsible for remembering and learning.
It also increased blood flow to the part of the brain responsible for decision-making.
The team from the University of College London says the results could provide better target therapies for those suffering from conditions that affect memory, such as Alzheimer's disease and post-traumatic stress disorder.
Researchers from University College London gave 15 participants with no history of cannabis use 600 mg of CBD, the main non-psychoactive ingredient in marijuana, on various occasions for a week and then 600 mg of a placebo
"To the best of our knowledge, this is the first study to find that CBD increases blood flow to key regions involved in memory processing, particularly the hippocampus," said lead author Dr. Michael Bloomfield, professor of psychiatry at UCL.
"This supports the view that CBD has region-specific effects on blood flow in the human brain, which was previously controversial."
CBD and tetrahydrocannabinol (THC) both come from the cannabis plant.
Together, they belong to the cannabinoid group of compounds found in hashish, hashish oil, and most varieties of marijuana.
THC is the psychoactive compound responsible for the euphoric, "high" feeling often associated with marijuana.
MRI scans showed that CBD increased blood flow to the hippocampus (second from left), which is responsible for memories, and to the orbitofrontal cortex (third from right), which is responsible for decision-making
The compound interacts with CB1 receptors in the central nervous system and brain, creating the sensations of euphoria and fear.
But CBD, which is not psychoactive, does not match well with these receptors and is believed to be responsible for some of the therapeutic effects of marijuana such as pain relief.
For the study, which was published in the Journal Journal of Psychopharmacology, the team recruited 15 young and healthy participants with no history of cannabis use.
Over the course of a week, the adults received 600 milligrams (mg) of oral cannabis or a placebo.
Then, seven days later, they received the capsule, which they did not take. The participants did not know which capsule they took on each occasion.
Next, the researchers used an MRI brain scanning technique called arterial spin labeling, which measures changes in blood oxygen levels.
The results showed that CBD significantly increased blood flow in the hippocampus and in the orbitofrontal cortex, with the latter playing a role in decision making.
"Cannabidiol is one of the main components of cannabis and is gaining interest in its therapeutic potential," said Bloomfield.
& # 39; There is evidence that CBD may help reduce symptoms of psychosis and anxiety. There is some evidence that CBD may improve memory function. & # 39;
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