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British scientists are testing a new Covid antibody therapy that could IMMEDIATELY give immunity to patients


A new antibody treatment with the potential to give people instant immunity and prevent disease after exposure to Covid-19 is being tested by British scientists in the UK.

The drug would offer immediate, long-term protection to patients when it was too late to offer a vaccine, which could potentially save thousands of lives.

It could be used as an emergency treatment for inpatients, nursing home residents, and college students to help reduce the spread of the virus.

People who live with someone who has caught or exposed to Covid could be injected with the drug to prevent infection, even if they haven't received a coronavirus vaccine.

British scientists at University College London Hospitals NHS (UCLH) have already injected ten people with the drug as part of the new Storm Chaser study to test the new treatment on 1,125 people worldwide. Participants received two consecutive doses of the drug.

They hope the treatment will provide protection from Covid-19 for anywhere from six months to a year.

The development came as:

  • England has registered 32,725 coronavirus cases in the past 24 hours, according to the latest figures, as festive bubbles have been canceled for millions.
  • The infections announced today mean cases have increased 14 percent in a week, even without the full numbers.
  • 570 deaths have been recorded in England, bringing the national number to 70,195 since March.
  • Nationwide numbers were not released today as decentralized nation numbers aren't counted on the government's dashboard over Christmas.
  • Six million more people moved into Tier 4 lockdown today after those who are already under the strictest coronavirus restrictions celebrated a Covid Christmas party as they could.
  • Sussex, Oxfordshire, Suffolk, Norfolk and Cambridgeshire will move into Tier 4 starting Saturday, which was developed in response to a variant of Covid-19 discovered in the UK.
  • The parts of Essex that are still in Tier 2, Waverley in Surrey and Hampshire, including Portsmouth and Southampton but with the exception of the New Forest, will also move up to the toughest tier.
  • The additional six million that go into Tier 4 brings the total number of people with the most severe restrictions to 24 million – 43 percent of the English population. Another 24.8 million will be in Tier 3.

A new antibody treatment with the potential to give people instant immunity and prevent disease after exposure to Covid-19 is being tested by British scientists in the UK (file photo)

A new antibody treatment with the potential to give people instant immunity and prevent disease after exposure to Covid-19 is being tested by British scientists in the UK (file photo)

UCLH scientists have also started a second clinical trial, called Provent, to investigate the use of the antibody in people who may not benefit from vaccines, such as: B. in patients with a weakened immune system or in people with an increased risk of Covid-19 infection on factors such as age and existing conditions.

UCLH injected the ten people – including medical staff and students – as part of the Storm Chaser trial at its new vaccine research center after the trial entered Phase 3 trials on Dec. 2.

The main groups in the study include healthcare workers, students who live in shared apartments and patients who have recently been exposed to those with Covid-19, as well as long-term care, military and industrial workers such as factory workers.

In the first study, the antibody known as AZD7442 was developed by pharmaceutical company AstraZeneca, which also worked with Oxford University to develop a vaccine that is pending approval by the Medicines and Health Products Regulatory Authority (MHRA).

In the meantime, the elderly and long-term carers, as well as those with conditions such as cancer and HIV, are being recruited to participate in the Provent study.

NHS England National Medical Director Professor Stephen Powis said: & # 39; The NHS's continued contribution to pioneering global efforts to fight Covid-19 is remarkable.

"These two clinical trials are important additions to testing new therapeutic approaches, as antibody treatments can provide an alternative to patient populations that may not benefit from a vaccine, such as immunocompromised patients."

UCLH virologist Dr. Catherine Houlihan, who leads the Storm Chaser study, said, “We know that this combination of antibodies can neutralize the virus. We therefore hope that giving this treatment by injection can provide immediate protection against the development of Covid-19. 19 for exposed people – if it were too late to offer a vaccine. & # 39;

Dr. Houlihan said the treatment is an "exciting addition" to efforts being tested and developed to fight the corovavirus, The Guardian reports.

"If we can show this treatment works and prevent people exposed to the virus from developing Covid-19, it would be an exciting addition to the arsenal of weapons being developed to fight this horrific virus," she said.

UCLH Infectious Disease Advisor, Dr. Nicky Longley, who heads the Provent part at the university, said, "We want to reassure anyone who a vaccine may not work for that we can offer an alternative that is equally protective."

Paul Hunter, professor of medicine at the University of East Anglia and an expert on infectious diseases, said the new treatment in the Storm Chaser study could save thousands of lives.

"If you have to deal with outbreaks in nursing homes or if you have patients who are at particularly high risk of severe Covid disease, such as B. the elderly, this can save many lives. Provided it's confirmed in phase 3 studies, it could play a big role in keeping people alive who would otherwise die. So it should be a big deal, ”he said.

"If you've had an outbreak in a nursing home, you may want to use these type of cocktails with antibodies to get the outbreak under control as soon as possible by giving the drug to everyone in the nursing home – residents and staff – who aren't to have." not been vaccinated.

"If you live with your elderly grandmother and you or someone else in the house becomes infected, you can give this to her too to protect her."

The potential breakthrough in immediate immunity treatment is welcome news for millions of Britons facing Tier 4 restrictions amid rising coronavirus cases.

The drug would offer immediate, long-term protection to patients when it was too late to offer a vaccine, which could potentially save thousands of lives. Pictured: Margaret Keenan, 90, greeted by staff when she returned to her ward after becoming the first person in the UK to receive the Pfizer / BioNtech vaccine for Covid-19 on December 8th

The drug would offer immediate, long-term protection to patients when it was too late to offer a vaccine, which could potentially save thousands of lives. Pictured: Margaret Keenan, 90, greeted by staff when she returned to her ward after becoming the first person in the UK to receive the Pfizer / BioNtech vaccine for Covid-19 on December 8th

The number of people with coronavirus in England rose to pre-second levels last week, with nearly 646,000 people infected

The number of people with coronavirus in England rose to pre-second levels last week, with nearly 646,000 people infected

England has posted 32,725 cases in the past 24 hours, according to the latest figures, when festive bubbles were canceled for millions.

Nationwide numbers were not released today as decentralized nation numbers aren't counted on the government's dashboard over Christmas.

The infections announced today mean cases have increased 14 percent in a week, even without the full numbers.

However, England has recorded 570 deaths, bringing the national number to 70,195 since March.

Last week, Christmas was canceled for millions of people in London, southeastern England and Wales, after Boris Johnson announced a new lockdown.

401 patients died of coronavirus in hospitals across England on Christmas Day. The grim number relating to hospital-related Covid-related deaths recorded in the past 24 hours is comparable to 317 a week ago.

None of the deaths were under 40 years old, and all but 14 had underlying health conditions, according to the latest data.

There have been another 33 deaths with coronavirus mentioned on the person's death certificate. This means that the total number of confirmed deaths reported in hospitals is now 48,150.

The 32,725 coronavirus cases announced in England today are up 14 percent from the 28,507 confirmed last Friday.

Northern Ireland didn't update its death toll yesterday. They will not resume until December 28th. No data are available for Wales as of December 25 or January 1.

In Scotland, death numbers are not updated until December 28th today. No figures will be available between January 1st and 4th.

More than 1,000 new cases of coronavirus were recorded in Scotland yesterday as measures eased over Christmas.

A total of 1,165 new cases have been reported by the Scottish government in the past 24 hours, new figures show.

The number is 4.3 percent of all tests performed during this period, compared with 5.3 percent the previous day.

A total of 118,035 cases have been reported in Scotland since the pandemic began.

During the holiday season, the COVID-19 dashboard, which publishes data on coronavirus cases and deaths, only uploads data for England on a daily basis.

The latest number comes as a new type of coronavirus in the south east of England. The strain is believed to spread better, but not yet more deadly.

One in 85 people in England is now infected with coronavirus, half of them caught the new superinfectious strain and cases in London have tripled in two weeks.

However, data from the Office for National Statistics (ONS) shows that the epidemic is triggered by southern regions where the variant has become the dominant tribe, with cases still persisting Flattening of the flattening in the north and in the Midlands, where it is not yet widespread.

Officials fear, however, that it is only a matter of time before the mutated variant – which is up to 56 percent more contagious than regular Covid and was first discovered in Kent in September – is spread everywhere.

Research has shown it became the dominant strain in the country in early November.

About two-thirds of people who tested positive in London, the east and the south-east are said to have the new variant, according to the ONS. Nationally it is believed that the strain accounts for 50 percent of infections.

Viruses mutate regularly, and scientists have found thousands of different mutations among samples of the virus that cause Covid-19.

However, many of these changes don't affect how easily the virus spreads or how severe the symptoms are.

Meanwhile, Prime Minister Boris Johnson surprisingly announced on December 19 that a new “Tier 4” would be introduced from midnight, effectively canceling Christmas for a third of the country over fears over Kent pollution.

Unnecessary shops, gyms, cinemas, hairdressers and bowling alleys have been closed – while people are only allowed to meet one other person from another household in a public outdoor area.

It meant thousands of Britons had to cancel their Christmas Day plans because it was no longer allowed to meet in a bubble.

In another blow to the British hoping for some normalcy in the future, Matt Hancock announced on Wednesday that a second mutant variant of the coronavirus has already been found in London and north-west England after being brought to the UK from South Africa.

Ministers fear that this variant, known as 501Y.V2, is even more contagious than the one in Kent, which is behind an explosion of coronavirus infections in the east, south-east and London.

Mr Hancock revealed that two cases of the South African variant have so far been discovered in England through contacts with people who had returned from the country in the past few weeks.

The cases had no link between them, one in London and the other in northwest England, as MailOnline understands, and the links with South Africa were discovered Tuesday.

Mr Hancock said the discovery of the variant in the UK was "very worrying" and revealed that "immediate restrictions" would be placed on travel to and from South Africa.

Those who have got out of the country in the past fourteen days are being asked to quarantine for two weeks.

He made the announcement when he plunged millions more people in southeast England into the fourth stage and began taking action at midnight on Christmas Day.

West Sussex and those parts of East Sussex, Essex, Surrey and Hampshire that are not yet in the top tier will enter tier 4 from one minute past midnight on Boxing Day, with the exception of the New Forest. Then there are Oxfordshire, Norfolk, Suffolk and Cambridgeshire.

Bristol, Gloucestershire, Somerset, Swindon, the Isle of Wight, the New Forest and Northamptonshire will move from Tier 2 to Tier 3, as will Cheshire and Warrington. And Cornwall and Herefordshire will enter Tier 2, which means that no part of England will be in the lowest Tier 1.

As the UK crisis deepened, SAGE experts found that the UK's coronavirus R rate rose to 1.1-1.3 due to the Kent variant of the coronavirus.

The strain is spreading fastest in London and east England, where the R could be as high as a shocking 1.5, and it's at least one or higher in every region of England except the Northeast and Northwest.

Yesterday, Boris Johnson refused to rule out a third national lockdown after a Sage model warned the UK must increase vaccination rates to avoid deaths from the mutated Kent coronavirus.

He warned people that the new Covid-19 strain "will continue to be difficult".

During a press conference, Mr. Johnson said, “We believe that we are now going to have to get through this difficult time with, as I have said many times, very strict restrictions and hard gradations.

“As much as I regret it, I think we need to fight this virus now to keep it from spiraling out of control in January.

"We need to take the time to get the vaccine into as many arms of the elderly and vulnerable as possible."

A very coveted Christmas: Six million MORE people are going into strict Tier 4 restrictions TODAY – bringing the total to 24 million – after the British have celebrated in every possible way

  • Sussex, Oxfordshire, Suffolk, Norfolk and Cambridgeshire switch to Tier 4 – created to stop the mutant strain
  • No household mix is ​​allowed in Tier 4, while all non-essential businesses and establishments must be closed again
  • It comes after many had to make the most of a Christmas Day that was already under Tier 4 restrictions in London

Millions of people will move into Tier 4 today after those already subject to the strictest coronavirus restrictions celebrated a Covid Christmas in every possible way.

Sussex, Oxfordshire, Suffolk, Norfolk and Cambridgeshire will move into Tier 4 starting Saturday, which was developed in response to a variant of Covid-19 discovered in the UK.

The parts of Essex that are still in Tier 2, Waverley in Surrey and Hampshire, including Portsmouth and Southampton but with the exception of the New Forest, will also move up to the toughest tier.

The additional six million that go into Tier 4 brings the total number of people with the most severe restrictions to 24 million – 43 percent of the English population. Another 24.8 million will be in Tier 3.

It comes after many had to make the most of a Christmas Day that was already under Tier 4 restrictions in London and the South East.

Two women brave the elements to have a socially distant Christmas dinner with all that entails on Clapham Common, London, which is in Tier 4

Two women brave the elements to have a socially distant Christmas dinner with all that entails on Clapham Common, London, which is in Tier 4

Four-year-old Archie receives socially distant gifts from his grandparents in Sutton Park in Sutton Coldfield, Birmingham on Christmas Day. Birmingham remains in Tier 3

Four-year-old Archie receives socially distant gifts from his grandparents in Sutton Park in Sutton Coldfield, Birmingham on Christmas Day. Birmingham remains in Tier 3

Some went to Brighton Beach to get some fresh air before climbing a step today. Brighton and Hove will move into Tier 4 on Boxing Day

Some went to Brighton Beach to get some fresh air before climbing a step today. Brighton and Hove will move into Tier 4 on Boxing Day

Sussex, Oxfordshire, Suffolk, Norfolk and Cambridgeshire will move into Tier 4 starting Saturday, which was developed in response to a variant of Covid-19 discovered in the UK

Sussex, Oxfordshire, Suffolk, Norfolk and Cambridgeshire will move into Tier 4 starting Saturday, which was developed in response to a variant of Covid-19 discovered in the UK

Photos showed groups gathering to have their Christmas dinner on Clapham Common in London while others headed to the beach in Brighton for some fresh air before moving up to level 4 today.

In other parts of the country, some families have been able to visit their elderly relatives in nursing homes for celebrations. Some families in Birmingham used to hang out with grandparents in parks to exchange gifts.

It came when England had 32,725 coronavirus cases in the past 24 hours, according to the latest figures, as festive bubbles were canceled for millions.

Nationwide numbers were not released today as decentralized nation numbers aren't counted on the government's dashboard over Christmas.

Families came to Brighton for a swim on the beach yesterday for traditional Christmas Day. The area will move to Tier 4 today

Families came to Brighton for a swim on the beach yesterday for traditional Christmas Day. The area will move to Tier 4 today

The infections announced today mean cases have increased 14 percent in a week, even without the full numbers.

However, England has recorded 570 deaths, bringing the national number to 70,195 since March.

Tier 4 does not allow household shuffling, although one person can meet another person outside in a public space while all non-essential stores and businesses are closed, including indoor personal hygiene and entertainment.

Nobody can enter or leave Tier 4 areas, and residents are not allowed to stay away from home overnight.

Meanwhile, Bristol, Gloucestershire, Somerset including North Somerset, Swindon, the Isle of Wight, the New Forest and Northamptonshire, and Cheshire and Warrington are advancing to Level 3.

Mary Orme (right) and her son Michael McKimm hug their mother and grandmother Rose McKimm during a Christmas Day visit to the Aspen Hill Village nursing home in Hunslet, Leeds. The nursing home can host nearly 50 visits for family members at Christmas after successful attempts with lateral flow tests for coronavirus

Mary Orme (right) and her son Michael McKimm hug their mother and grandmother Rose McKimm during a Christmas Day visit to the Aspen Hill Village nursing home in Hunslet, Leeds. The nursing home can host nearly 50 visits for family members at Christmas after successful attempts with lateral flow tests for coronavirus

Some families in Birmingham used to hang out with grandparents in parks to exchange gifts. This family does this while socially distancing themselves

Some families in Birmingham used to hang out with grandparents in parks to exchange gifts. This family does this while socially distancing themselves

Swimmers take a dip in Blackroot Pool in Sutton Park in Sutton Coldfield, Birmingham on Christmas Day. The area remains in Tier 3

Swimmers take a dip in Blackroot Pool in Sutton Park in Sutton Coldfield, Birmingham on Christmas Day. The area remains in Tier 3

Photos showed groups gathering today to have their Christmas dinner on Clapham Common in London as the city is in Tier 4

Photos showed groups gathering today to have their Christmas dinner on Clapham Common in London as the city is in Tier 4

Four-year-old Archie receives socially distant gifts from his grandparents in Sutton Park in Sutton Coldfield, Birmingham

Four-year-old Archie receives socially distant gifts from his grandparents in Sutton Park in Sutton Coldfield, Birmingham

Many came to Brighton today for the traditional Christmas Day swimming at the beach before the city moves into Tier 4 restrictions today

Many came to Brighton today for the traditional Christmas Day swimming at the beach before the city moves into Tier 4 restrictions today

Albie, Clive and their father Hudson take a dip in the sea on Christmas Day in Saltdean, East Sussex today. The area will move to Tier 4 starting today

Albie, Clive and their father Hudson take a dip in the sea on Christmas Day in Saltdean, East Sussex today. The area will move to Tier 4 starting today

In the "very high" alert level, mixing indoor and outdoor households is only permitted in parks and public gardens.

All hospitality is closed, with the exception of food stalls and deliveries, and accommodations and entertainment venues must be closed.

Cornwall and Herefordshire will move up to Tier 2 from December 26th, where the main restrictions are that mixing of households is not permitted indoors but the “rule of six” applies outdoors.

Eating places must close unless they serve extensive meals with drinks, while large sporting and entertainment events are permitted with a very limited audience.

The Isles of Scilly, with a population of just 2,000, will be the only area of ​​England remaining in Tier 1.

At the lowest alarm level, the “rule of six” must apply inside and outside, while table service must be offered in restaurants, with the last orders placed at 10 p.m. and the closing time at 11 p.m.

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